Positively False - Birth of a Heresy traces the challenge over the past 25 years to the scientific orthodoxy which maintains that HIV is the cause of AIDS. Joan Shenton reaches back to 1987 through her extensive archive of broadcast and non-broadcast video material and combines it with current footage. She shows how dissident scientists, journalists and activists have voiced their concerns about the way the infectious hypothesis for AIDS took over from the toxic one and highlights the impact the dogma surrounding a viral cause for AIDS has had on people's lives. The film travels through Africa, Europe and the United States revealing the way plague terror, financial objectives and scientific skulduggery have led to tragic examples of toxicity and death from antiviral drugs, social stigma, broken families, fear of sex, homophobia and imprisonment.